USE OF INNOVATIVE TECHNOLOGIES IN THE EARLY DIAGNOSIS OF YELLOW FEVER

Authors

DOI:

https://doi.org/10.5281/zenodo.15015193

Keywords:

Biossensores, Febre Amarela, Diagnóstico Precoce, PCR, Tecnologias Inovadoras.

Abstract

Yellow fever is a severe viral disease transmitted by mosquitoes of the Aedes and Haemagogus genera, prevalent in tropical regions, especially in Latin America and Africa. Although the vaccine against the disease has been highly effective and available since 1937, recurrent outbreaks continue to occur, resulting in many deaths. Early diagnosis is crucial for proper treatment and epidemiological control, as the disease can progress to severe and hemorrhagic forms. However, conventional diagnostic methods, such as serology and viral isolation, have limitations, particularly in the early stages when symptoms are nonspecific and difficult to differentiate from other diseases. In this context, the use of innovative technologies has shown promise in overcoming these limitations. Molecular techniques, such as real-time PCR, can detect the virus's RNA even at low concentrations, providing fast and accurate results. Biosensors using nanomaterials such as graphene and gold nanoparticles offer high sensitivity and can be used in the field, making diagnosis more accessible, especially in hard-to-reach areas. Artificial intelligence (AI) also plays a significant role, enabling the analysis of large volumes of clinical and epidemiological data, which helps predict outbreaks and screen cases. Additionally, portable rapid diagnostic devices and digital monitoring platforms have expanded real-time response capabilities, facilitating public health management. Despite these promising advancements, large-scale implementation of these technologies still faces challenges, such as high costs, limited infrastructure, and the need for trained professionals. The effectiveness of these innovations depends on several factors, including resource availability and adaptation to local realities, particularly in remote areas with limited access to healthcare services. Thus, effective public policies and a coordinated effort between governments, international organizations, and research institutions are essential to ensuring the widespread and equitable use of these technologies. The combination of early diagnosis with rapid interventions can not only reduce yellow fever mortality but also enhance prevention and control strategies, contributing to a more effective and sustainable approach to tackling the disease.

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Author Biographies

  • Azize Capucho Jorge , Brazilian College of Education Multivix

    Graduated in Medicine from the Brazilian Faculty of Education Multivix, Generalist Specialty

  • Filipe Monteiro Beltrão, Estácio School of Medicine in Juazeiro do Norte

    Graduated in Medicine from the Estácio de Juazeiro do Norte School of Medicine

  • Elisabete Soares de Santana, Holy Trinity College - FAST

    Undergraduate in Pharmacy at the Santíssima Trindade College - FAST

  • Jose Adeilson Da Silva, Recife University Center - UNIPESU

    Undergraduate in Biomedicine at the Recife University Center - UNIPESU

  • Emanuelly Ferrari, UNIEURO

    Undergraduate in Medicine at UNIEURO

  • Bruna Nunes Mendes , FAMENE

    Graduated in Medicine from FAMENE

  • Rafael Alvarenga da Silva , Federal University of Rio Grande do Norte

    Undergraduate in Medicine from the Federal University of Rio Grande do Norte

  • Filipe Nunes Mendes, Olinda School of Medicine - FMO

    Graduated in Medicine from the Faculty of Medicine of Olinda - FMO

References

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Published

2025-04-11

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How to Cite

USE OF INNOVATIVE TECHNOLOGIES IN THE EARLY DIAGNOSIS OF YELLOW FEVER (A. Capucho Jorge, F. Monteiro Beltrão, E. S. De Santana, J. A. Da Silva, E. Ferrari, B. Nunes Mendes, R. A. . Da Silva, & F. Nunes Mendes , Trans.). (2025). Periodicos Cedigma, 1(2), 11-18. https://doi.org/10.5281/zenodo.15015193

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